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| Model | Years | Speeds | Drive Train | Trans Model |
| Fusion S, SE, SEL | 2006-2009 | 5 Spd | FWD, AWD 2.3L L4 | FNR5 |
| Fusion S, SE, SEL | 2006-2010 | 6 Spd | FWD, AWD 3.0L V6 | AF21, TF-81SC |
| Fusion Sport | 2009-2012 | 6 Spd | FWD, AWD 3.5L V6 Turbo, | 6F50 |
| Fusion S, SE, SEL, Titanium, Platinum, Sport | 2009-2020 | 6 Spd | FWD, AWD 1.5L L4, 1.6L L4 Turbo, 2.0L L4 Turbo, 2.5L L4, 2.7L L4 | 6F35 |
| Fusion Hybrid | 2010-2012 | CVT | FWD 2.5 Liter L4 FULL HYBRID EV-Gas (FHEV) | CF35 |
| Fusion Hybrid, Energi SE, Energi Titanium, SE Hybrid, S Hybrid, Platinum Titanium Hybrid, Energi Titanium | 2013-2020 | CVT | FWD 2.0 Liter L4 PLUG-IN HYBRID EV-Gas (PHEV | HF35 |